Endocrine Abstracts

Introduction: Simultaneous pancreas-kidney transplantation (SPKT) is the best way to restore normoglycemia and renal function in patients with type 1 diabetes mellitus (T1D) and end-stage renal disease (ESRD). Pregnant patients after SPKT are a high-risk group for adverse events/loss fetal and transplantation organs. These risks are significantly reduced due to pregnancy planning, regular monitoring of the woman and fetus condition with timely correction of immunosuppressive t...

Introduction: Today simultaneous pancreas-kidney transplantation (SPKT) is an effective method of treatment for patients with type 1 diabetes mellitus (T1D) and terminal stage of diabetic nephropathy (DN) on renal replacement therapy by hemodialysis. It solves several problems: reduces the severity of intoxication syndrome, contributes to the achievement of euglycemia in most cases, that allows to delay progression of micro- and macrovascular diabetic complications. Case Descr...

BackgroundThe kidney or kidney-pancreas transplantation corrects many of the metabolic or biochemical abnormalities associated with chronic kidney disease (CKD); however, mineral bone disease (MBD) and cardiovascular pathology remain frequent in transplant recipients. This happens especially in patients who have long history of secondary hyperparathyroidism (SHPT), as well immunosuppressive therapy plays an important role in the progression of MBD.<p...